4OVA

Structure of the two tandem Tudor domains and a new identified KH0 domain from human Fragile X Mental Retardation Protein

Summary for 4OVA

• Entry DOI: 10.2210/pdb4ova/pdb
• Related: 2qnd
• Descriptor: Fragile X mental retardation protein 1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• Functional Keywords: kh domain, fragile x mental retardation protein, fmrp, tandem tudor domains, eukaryotic kh domains, kh0 domain, rna binding protein, protein interaction
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q06787
• Total number of polymer chains: 4
• Total formula weight: 97495.18

Authors

Chen, Z.H.,Chen, Z.Z. (deposition date: 2014-02-21, release date: 2015-02-25, Last modification date: 2023-11-08)

• Primary citation: Hu, Y.,Chen, Z.H.,Fu, Y.,He, Q.,Jiang, L.,Zheng, J.,Gao, Y.,Mei, P.,Chen, Z.Z.,Ren, X.; The amino-terminal structure of human fragile X mental retardation protein obtained using precipitant-immobilized imprinted polymers; Nat Commun, 6:6634-6634, 2015; PubMed: 25799254; DOI: 10.1038/ncomms7634

Experimental method

X-RAY DIFFRACTION (3 Å)