4OLB

Crystal Structure of Human Argonaute2 Bound to Tryptophan

Replaces:  4EI3

Summary for 4OLB

• Entry DOI: 10.2210/pdb4olb/pdb
• Related: 4OLA
• Descriptor: Protein argonaute-2, 5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*U)-3', TRYPTOPHAN, ... (4 entities in total)
• Functional Keywords: rna-binding protein, rna interference, protein-rna complex, ago, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, P-body: Q9UKV8
• Total number of polymer chains: 2
• Total formula weight: 101010.69

Authors

Schirle, N.T.,MacRae, I.J. (deposition date: 2014-01-23, release date: 2014-02-05, Last modification date: 2023-09-20)

• Primary citation: Schirle, N.T.,MacRae, I.J.; The crystal structure of human Argonaute2.; Science, 336:1037-1040, 2012; PubMed: 22539551; DOI: 10.1126/science.1221551

Experimental method

X-RAY DIFFRACTION (2.899 Å)