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4OFR

Crystal structure of AR-LBD bound with co-regulator peptide

Summary for 4OFR
Entry DOI10.2210/pdb4ofr/pdb
Related4OEA 4OED 4OEY 4OEZ 4OFU 4OGH 4OH5 4OH6 4OHA 4OIL 4OIU 4OJ9 4OJB 4OK1 4OKB 4OKT 4OKW 4OKX 4OLM
DescriptorAndrogen receptor, co-regulator peptide, 5-ALPHA-DIHYDROTESTOSTERONE, ... (4 entities in total)
Functional Keywordsalpha-helix, hormone/growth factor receptor, phosphorylation, hormone receptor-peptide complex, hormone receptor/peptide
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: P10275
Total number of polymer chains2
Total formula weight30799.98
Authors
Liu, J.S.,Hsu, C.L.,Wu, W.G. (deposition date: 2014-01-15, release date: 2014-08-20, Last modification date: 2023-09-20)
Primary citationHsu, C.L.,Liu, J.S.,Wu, P.L.,Guan, H.H.,Chen, Y.L.,Lin, A.C.,Ting, H.J.,Pang, S.T.,Yeh, S.D.,Ma, W.L.,Chen, C.J.,Wu, W.G.,Chang, C.
Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8:1575-1587, 2014
Cited by
PubMed: 25091737
DOI: 10.1016/j.molonc.2014.06.009
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.26 Å)
Structure validation

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