4O9W

Crystal structure of polo-like kinase(PLK1)PBD in complex with phospho peptide

Summary for 4O9W

Entry DOI	10.2210/pdb4o9w/pdb
Descriptor	Serine/threonine-protein kinase PLK1, phospho peptide VAL-LEU-SER-TPO-LEU-NH2 (3 entities in total)
Functional Keywords	polo-box domain, transferase-peptide complex, transferase/peptide
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	26362.06
Authors	Bong, S.M.,Lee, B.I.,Kim, K.T. (deposition date: 2014-01-03, release date: 2014-08-13, Last modification date: 2019-12-18)
Primary citation	Kim, J.H.,Shim, J.,Ji, M.J.,Jung, Y.,Bong, S.M.,Jang, Y.J.,Yoon, E.K.,Lee, S.J.,Kim, K.G.,Kim, Y.H.,Lee, C.,Lee, B.I.,Kim, K.T. The condensin component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores. Nat Commun, 5:4588-4588, 2014 Cited by PubMed: 25109385 DOI: 10.1038/ncomms5588 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.694 Å)

Structure validation