4O7Q

Crystal Structure of the F27G AIM2 Pyrin Domain Mutant and Similarities of its Self-association to DED/DED Interactions

Summary for 4O7Q

Entry DOI	10.2210/pdb4o7q/pdb
Descriptor	Interferon-inducible protein AIM2 (2 entities in total)
Functional Keywords	pyd/dd, signal transduction, inflammasome, signaling protein, apoptosis
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	10839.63
Authors	Lu, A.,Kabaleeswaran, V.,Wu, H. (deposition date: 2013-12-26, release date: 2014-02-19, Last modification date: 2024-04-03)
Primary citation	Lu, A.,Kabaleeswaran, V.,Fu, T.,Magupalli, V.G.,Wu, H. Crystal Structure of the F27G AIM2 PYD Mutant and Similarities of Its Self-Association to DED/DED Interactions. J.Mol.Biol., 426:1420-1427, 2014 Cited by PubMed: 24406744 DOI: 10.1016/j.jmb.2013.12.029 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation