4O3T

Zymogen HGF-beta/MET with Zymogen Activator Peptide ZAP.14

Summary for 4O3T

• Entry DOI: 10.2210/pdb4o3t/pdb
• Descriptor: Hepatocyte growth factor, Hepatocyte growth factor receptor, ZAP.14, ... (5 entities in total)
• Functional Keywords: trypsin homology, receptor activation, transferase-growth factor complex, transferase/growth factor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 91646.41

Authors

Eigenbrot, C.,Landgraf, K.E.,Steffek, M. (deposition date: 2013-12-18, release date: 2014-06-04, Last modification date: 2023-09-20)

• Primary citation: Landgraf, K.E.,Steffek, M.,Quan, C.,Tom, J.,Yu, C.,Santell, L.,Maun, H.R.,Eigenbrot, C.,Lazarus, R.A.; An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides.; Nat.Chem.Biol., 10:567-573, 2014; PubMed: 24859116; DOI: 10.1038/nchembio.1533

Experimental method

X-RAY DIFFRACTION (2.99 Å)