4NQX

Crystal Structure of HLA A*0101 in complex with NP44-S7N, an 9-mer influenza epitope

Summary for 4NQX

Entry DOI	10.2210/pdb4nqx/pdb
Related	4NQV
Descriptor	HLA class I histocompatibility antigen, A-1 alpha chain, Beta-2-microglobulin, NP44-S7N mutant peptide, CTELKLNDY, ... (4 entities in total)
Functional Keywords	immune system, presenting viral epitope, t cell receptor, immune system-viral protein complex, immune system/viral protein
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P30443 Secreted: P61769
Total number of polymer chains	18
Total formula weight	274090.48
Authors	Rossjohn, J.,Gras, S. (deposition date: 2013-11-26, release date: 2013-12-25, Last modification date: 2023-09-20)
Primary citation	Quinones-Parra, S.,Grant, E.,Loh, L.,Nguyen, T.H.,Campbell, K.A.,Tong, S.Y.,Miller, A.,Doherty, P.C.,Vijaykrishna, D.,Rossjohn, J.,Gras, S.,Kedzierska, K. Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities. Proc.Natl.Acad.Sci.USA, 111:1049-1054, 2014 Cited by PubMed: 24395804 DOI: 10.1073/pnas.1322229111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation