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4NQE

Crystal structure of TCR-MR1 ternary complex bound to 5-(2-oxoethylideneamino)-6-D-ribitylaminouracil

Summary for 4NQE
Entry DOI10.2210/pdb4nqe/pdb
Related4NQC 4NQD
DescriptorMajor histocompatibility complex class I-related gene protein, Beta-2-microglobulin, TCR alpha, ... (6 entities in total)
Functional Keywordsimmune complex, mr1, tcr, ig-domain, protein binding, schiff base, membrane, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains8
Total formula weight187945.46
Authors
Birkinshaw, R.W.,Rossjohn, J. (deposition date: 2013-11-25, release date: 2014-04-16, Last modification date: 2020-02-19)
Primary citationCorbett, A.J.,Eckle, S.B.,Birkinshaw, R.W.,Liu, L.,Patel, O.,Mahony, J.,Chen, Z.,Reantragoon, R.,Meehan, B.,Cao, H.,Williamson, N.A.,Strugnell, R.A.,Van Sinderen, D.,Mak, J.Y.,Fairlie, D.P.,Kjer-Nielsen, L.,Rossjohn, J.,McCluskey, J.
T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Nature, 509:361-365, 2014
Cited by
PubMed: 24695216
DOI: 10.1038/nature13160
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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