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4NCO

Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122

Summary for 4NCO
Entry DOI10.2210/pdb4nco/pdb
Related3J5M 4JY4 4JY5 4JY6
Related PRD IDPRD_900111
DescriptorBG505 SOSIP gp120, BG505 SOSIP gp41, PGT122 light chain, ... (8 entities in total)
Functional Keywordstype-1 membrane fusion glycoprotein trimer, hiv-1 envelope, gp120, gp41, membrane fusion, viral entry, cd4, ccr5/cxcr4, broadly neutralizing antibodies, viral surface, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains12
Total formula weight350934.77
Authors
Julien, J.-P.,Stanfield, R.L.,Lyumkis, D.,Ward, A.B.,Wilson, I.A. (deposition date: 2013-10-24, release date: 2013-11-13, Last modification date: 2023-09-20)
Primary citationJulien, J.P.,Cupo, A.,Sok, D.,Stanfield, R.L.,Lyumkis, D.,Deller, M.C.,Klasse, P.J.,Burton, D.R.,Sanders, R.W.,Moore, J.P.,Ward, A.B.,Wilson, I.A.
Crystal structure of a soluble cleaved HIV-1 envelope trimer.
Science, 342:1477-1483, 2013
Cited by
PubMed: 24179159
DOI: 10.1126/science.1245625
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (4.7 Å)
Structure validation

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