4N9A

E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid

Summary for 4N9A

Entry DOI	10.2210/pdb4n9a/pdb
Related	4N94 4N95 4N96 4N97 4N98 4N99
Descriptor	DNA polymerase III subunit beta, CALCIUM ION, TETRAETHYLENE GLYCOL, ... (7 entities in total)
Functional Keywords	poliii beta, sliding clamp, dnan, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Escherichia coli
Cellular location	Cytoplasm: P0A988
Total number of polymer chains	2
Total formula weight	82188.47
Authors	Yin, Z.,Oakley, A.J. (deposition date: 2013-10-19, release date: 2013-11-06, Last modification date: 2023-09-20)
Primary citation	Yin, Z.,Whittell, L.R.,Wang, Y.,Jergic, S.,Liu, M.,Harry, E.J.,Dixon, N.E.,Beck, J.L.,Kelso, M.J.,Oakley, A.J. Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57:2799-2806, 2014 Cited by PubMed: 24592885 DOI: 10.1021/jm500122r PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation