Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4MZ6

Structure of importin-alpha: dUTPase S11E NLS mutant complex

Replaces:  4FDS
Summary for 4MZ6
Entry DOI10.2210/pdb4mz6/pdb
Related1ELJ 3UKW 4MZ5
DescriptorDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 (3 entities in total)
Functional Keywordsarm repeat, protein transport, importin, nucleus
Biological sourceMus musculus (mouse)
More
Cellular locationCytoplasm (By similarity): P33316
Isoform 2: Nucleus. Isoform 3: Mitochondrion: P52293
Total number of polymer chains3
Total formula weight57974.58
Authors
Marfori, M.,Rona, G.,Vertessy, B.G.,Kobe, B. (deposition date: 2013-09-29, release date: 2013-11-13, Last modification date: 2024-02-28)
Primary citationRona, G.,Marfori, M.,Borsos, M.,Scheer, I.,Takacs, E.,Toth, J.,Babos, F.,Magyar, A.,Erdei, A.,Bozoky, Z.,Buday, L.,Kobe, B.,Vertessy, B.G.
Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69:2495-2505, 2013
Cited by
PubMed: 24311590
DOI: 10.1107/S0907444913023354
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.88 Å)
Structure validation

218196

PDB entries from 2024-04-10

PDB statisticsPDBj update infoContact PDBjnumon