4MP0

Structure of a second nuclear PP1 Holoenzyme, crystal form 2

Summary for 4MP0

Entry DOI	10.2210/pdb4mp0/pdb
Related	3V4Y 4MOY
Descriptor	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, Serine/threonine-protein phosphatase 1 regulatory subunit 10, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywords	serine/threonine phosphatase, nucleus, hydrolase
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P62136 Nucleus (By similarity): O55000
Total number of polymer chains	4
Total formula weight	79355.92
Authors	Choy, M.S.,Hieke, M.,Peti, W.,Page, R. (deposition date: 2013-09-12, release date: 2014-03-26, Last modification date: 2024-02-28)
Primary citation	Choy, M.S.,Hieke, M.,Kumar, G.S.,Lewis, G.R.,Gonzalez-Dewhitt, K.R.,Kessler, R.P.,Stein, B.J.,Hessenberger, M.,Nairn, A.C.,Peti, W.,Page, R. Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code. Proc.Natl.Acad.Sci.USA, 111:4097-4102, 2014 Cited by PubMed: 24591642 DOI: 10.1073/pnas.1317395111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1003 Å)

Structure validation