4MLP

Mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase

Summary for 4MLP

Entry DOI	10.2210/pdb4mlp/pdb
Related	4I6E 4I6G 4I6J
Descriptor	Cryptochrome-2, N-[(2S)-3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-(furan-2-ylmethyl)methanesulfonamide (3 entities in total)
Functional Keywords	photolyase homology region, transcriptional repressor, period, fbxl3, clock, nucleus, transcription
Biological source	Mus musculus (mouse)
Cellular location	Cytoplasm: Q9R194
Total number of polymer chains	4
Total formula weight	236350.09
Authors	Nangle, S.,Xing, W.,Zheng, N. (deposition date: 2013-09-06, release date: 2013-10-16, Last modification date: 2023-09-20)
Primary citation	Nangle, S.,Xing, W.,Zheng, N. Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase. Cell Res., 23:1417-1419, 2013 Cited by PubMed: 24080726 DOI: 10.1038/cr.2013.136 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.943 Å)

Structure validation