4MHG

Crystal structure of ETV6 bound to a specific DNA sequence

Summary for 4MHG

• Entry DOI: 10.2210/pdb4mhg/pdb
• Related: 2LF7 2LF8
• Descriptor: Specific 14 bp DNA, Complementary Specific 14 bp DNA, Transcription factor ETV6, ... (4 entities in total)
• Functional Keywords: ets domain, transcription factor, transcription-dna complex, transcription/dna
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 3
• Total formula weight: 21011.94

Authors

Chan, A.C.,De, S.,Coyne III, H.J.,Okon, M.,Murphy, M.E.,Graves, B.J.,McIntosh, L.P. (deposition date: 2013-08-29, release date: 2014-01-08, Last modification date: 2024-02-28)

• Primary citation: De, S.,Chan, A.C.,Coyne, H.J.,Bhachech, N.,Hermsdorf, U.,Okon, M.,Murphy, M.E.,Graves, B.J.,McIntosh, L.P.; Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.; J.Mol.Biol., 426:1390-1406, 2014; PubMed: 24333486; DOI: 10.1016/j.jmb.2013.11.031

Experimental method

X-RAY DIFFRACTION (2.199 Å)