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4MGD

Crystal structure of hERa-LBD (Y537S) in complex with HPTE

Summary for 4MGD
Entry DOI10.2210/pdb4mgd/pdb
Related3UU7 3UUA 3UUC 3UUD 4MG5 4MG6 4MG7 4MG8 4MG9 4MGA 4MGB 4MGC
DescriptorEstrogen receptor, Nuclear receptor coactivator 1, 4,4'-(2,2,2-trichloroethane-1,1-diyl)diphenol, ... (7 entities in total)
Functional Keywordsligand-binding domain of nuclear hormone receptor, hormone receptor
Biological sourceHomo sapiens (human)
More
Cellular locationIsoform 1: Nucleus . Isoform 3: Nucleus. Nucleus: P03372 P03372
Nucleus : Q15788
Total number of polymer chains4
Total formula weight62097.55
Authors
Delfosse, V.,Grimaldi, M.,Bourguet, W. (deposition date: 2013-08-28, release date: 2014-09-03, Last modification date: 2023-12-06)
Primary citationDelfosse, V.,Grimaldi, M.,Cavailles, V.,Balaguer, P.,Bourguet, W.
Structural and functional profiling of environmental ligands for estrogen receptors.
Environ.Health Perspect., 122:1306-1313, 2014
Cited by
PubMed: 25260197
DOI: 10.1289/ehp.1408453
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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