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4MEX

Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A

Summary for 4MEX
Entry DOI10.2210/pdb4mex/pdb
Related4MEY
Related PRD IDPRD_001162
DescriptorDNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywordsrna polymerase, dna binding, transferase-antibiotic complex, transferase/antibiotic
Biological sourceEscherichia coli
More
Cellular locationCytoplasm (Potential): P00579
Total number of polymer chains14
Total formula weight925551.65
Authors
Feng, Y.,Zhang, Y.,Arnold, E.,Ebright, R.H. (deposition date: 2013-08-27, release date: 2014-05-21, Last modification date: 2014-06-25)
Primary citationDegen, D.,Feng, Y.,Zhang, Y.,Ebright, K.Y.,Ebright, Y.W.,Gigliotti, M.,Vahedian-Movahed, H.,Mandal, S.,Talaue, M.,Connell, N.,Arnold, E.,Fenical, W.,Ebright, R.H.
Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3:e02451-e02451, 2014
Cited by
PubMed: 24843001
DOI: 10.7554/eLife.02451
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.902 Å)
Structure validation

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