4MEL

Crystal Structure of the human USP11 DUSP-UBL domains

Summary for 4MEL

• Entry DOI: 10.2210/pdb4mel/pdb
• Related: 4MEM
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 11 (2 entities in total)
• Functional Keywords: domain present in ubiquitin specific proteases (dusp), ubiquitin-like domain (ubl), deubiquitinating enzyme, dub, du finger, ubiquitin thiolesterase, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P51784
• Total number of polymer chains: 2
• Total formula weight: 53609.72

Authors

Harper, S.,Gratton, H.E.,Cornaciu, I.,Oberer, M.,Scott, D.J.,Emsley, J.,Dreveny, I. (deposition date: 2013-08-27, release date: 2014-05-07, Last modification date: 2023-09-20)

• Primary citation: Harper, S.,Gratton, H.E.,Cornaciu, I.,Oberer, M.,Scott, D.J.,Emsley, J.,Dreveny, I.; Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains.; Biochemistry, 53:2966-2978, 2014; PubMed: 24724799; DOI: 10.1021/bi500116x

Experimental method

X-RAY DIFFRACTION (2.899 Å)