4M8Z

Crystal Structure of SFH3, a phosphatidylinositol transfer protein that integrates phosphoinositide signaling with lipid droplet metabolism

Summary for 4M8Z

Entry DOI	10.2210/pdb4m8z/pdb
Descriptor	Phosphatidylinositol transfer protein PDR16 (2 entities in total)
Functional Keywords	lipid droplets, phosphoinositides, meiosis, cral trio, sec14, phospholipid signaling, signaling protein
Biological source	Saccharomyces cerevisiae S288c (Baker's yeast)
Total number of polymer chains	2
Total formula weight	82026.84
Authors	Ortlund, E.O.,Pathak, M.C. (deposition date: 2013-08-14, release date: 2014-09-10, Last modification date: 2019-07-17)
Primary citation	Ren, J.,Pei-Chen Lin, C.,Pathak, M.C.,Temple, B.R.,Nile, A.H.,Mousley, C.J.,Duncan, M.C.,Eckert, D.M.,Leiker, T.J.,Ivanova, P.T.,Myers, D.S.,Murphy, R.C.,Brown, H.A.,Verdaasdonk, J.,Bloom, K.S.,Ortlund, E.A.,Neiman, A.M.,Bankaitis, V.A. A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis. Mol Biol Cell, 25:712-727, 2014 Cited by PubMed: 24403601 DOI: 10.1091/mbc.E13-11-0634 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.928 Å)

Structure validation