4M8G

Crystal structure of Se-Met hN33/Tusc3

Summary for 4M8G

Entry DOI	10.2210/pdb4m8g/pdb
Related	4M90 4M91 4M92
Descriptor	Tumor suppressor candidate 3 (2 entities in total)
Functional Keywords	thioredoxin-like fold; thiol/disulfide oxidoreductase, thiol/disulfide exchange reactions, redox-active protein, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity): Q13454
Total number of polymer chains	2
Total formula weight	38940.27
Authors	Mohorko, E.,Owen, R.L.,Malojcic, G.,Brozzo, M.S.,Aebi, M.,Glockshuber, R. (deposition date: 2013-08-13, release date: 2014-03-26, Last modification date: 2014-05-07)
Primary citation	Mohorko, E.,Owen, R.L.,Malojcic, G.,Brozzo, M.S.,Aebi, M.,Glockshuber, R. Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation. Structure, 22:590-601, 2014 Cited by PubMed: 24685145 DOI: 10.1016/j.str.2014.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation