4M76
Integrin I domain of complement receptor 3 in complex with C3d
Summary for 4M76
| Entry DOI | 10.2210/pdb4m76/pdb |
| Descriptor | Complement C3, Integrin alpha-M, NICKEL (II) ION, ... (4 entities in total) |
| Functional Keywords | integrin, complement receptor, immunity, innate immunity, inflammation, phagocytosis, mac-1, cd11b/cd18, alphambeta2, macrophage, rossmann fold, i domain, von willebrand factor a (vwa), alpha-alpha barrel, adhesion, cell adhesion |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted: P01024 Membrane; Single-pass type I membrane protein: P11215 |
| Total number of polymer chains | 2 |
| Total formula weight | 55796.98 |
| Authors | Bajic, G.,Yatime, L.,Vorup-Jensen, T.,Andersen, G.R. (deposition date: 2013-08-12, release date: 2013-10-02, Last modification date: 2023-09-20) |
| Primary citation | Bajic, G.,Yatime, L.,Sim, R.B.,Vorup-Jensen, T.,Andersen, G.R. Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3. Proc.Natl.Acad.Sci.USA, 110:16426-16431, 2013 Cited by PubMed: 24065820DOI: 10.1073/pnas.1311261110 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.804 Å) |
Structure validation
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