4M4R

Epha4 ectodomain complex with ephrin a5

Summary for 4M4R

• Entry DOI: 10.2210/pdb4m4r/pdb
• Related: 4M4P
• Descriptor: Ephrin type-A receptor 4, Ephrin-A5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: eph receptor ephrin complex, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 299849.70

Authors

Xu, K.,Tsvetkova-Robev, D.,Xu, Y.,Goldgur, Y.,Chan, Y.-P.,Himanen, J.P.,Nikolov, D.B. (deposition date: 2013-08-07, release date: 2013-10-30, Last modification date: 2023-09-20)

• Primary citation: Xu, K.,Tzvetkova-Robev, D.,Xu, Y.,Goldgur, Y.,Chan, Y.P.,Himanen, J.P.,Nikolov, D.B.; Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.; Proc.Natl.Acad.Sci.USA, 110:14634-14639, 2013; PubMed: 23959867; DOI: 10.1073/pnas.1311000110

Experimental method

X-RAY DIFFRACTION (3.13 Å)