4LQ9

Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2

Summary for 4LQ9

Entry DOI	10.2210/pdb4lq9/pdb
Related	4LQ3
Descriptor	RNA-dependent RNA-polymerase, naphthalene-1,5-disulfonic acid, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	rna-dependent-rna-polymerase, rdrp-inhibotir complex, viral protein-replication inhibitor complex, viral protein/replication inhibitor
Biological source	Norovirus
Total number of polymer chains	1
Total formula weight	59258.66
Authors	Milani, M.,Tarantino, D.,Mastrangelo, E.,Croci, R. (deposition date: 2013-07-17, release date: 2014-02-12, Last modification date: 2024-02-28)
Primary citation	Tarantino, D.,Pezzullo, M.,Mastrangelo, E.,Croci, R.,Rohayem, J.,Robel, I.,Bolognesi, M.,Milani, M. Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase. Antiviral Res., 102:23-28, 2014 Cited by PubMed: 24316032 DOI: 10.1016/j.antiviral.2013.11.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation