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4LOE

Human p53 Core Domain Mutant N239Y

Replaces:  2QXC
Summary for 4LOE
Entry DOI10.2210/pdb4loe/pdb
Related4KVP 4LO9 4LOF
DescriptorCellular tumor antigen p53, ZINC ION (3 entities in total)
Functional Keywordsbeta sandwich, tumor suppressor, dna binding, nuclear, apoptosis
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total formula weight98805.43
Authors
Wallentine, B.D.,Wang, Y.,Luecke, H. (deposition date: 2013-07-12, release date: 2013-07-31, Last modification date: 2023-09-20)
Primary citationWallentine, B.D.,Wang, Y.,Tretyachenko-Ladokhina, V.,Tan, M.,Senear, D.F.,Luecke, H.
Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.
Acta Crystallogr.,Sect.D, 69:2146-2156, 2013
Cited by
PubMed: 24100332
DOI: 10.1107/S0907444913020830
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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