4LIX

Crystal structure of ent-copalyl diphosphate synthase from Arabidopsis thaliana in complex with (S)-15-aza-14,15-dihydrogeranylgeranyl thiolodiphosphate at 1.55 A resolution

Summary for 4LIX

Entry DOI	10.2210/pdb4lix/pdb
Related	3PYA 3PYB
Descriptor	Ent-copalyl diphosphate synthase, chloroplastic, S-[(2E,6E,10E)-14-(dimethylamino)-3,7,11-trimethyltetradeca-2,6,10-trien-1-yl] trihydrogen thiodiphosphate, PHOSPHATE ION, ... (5 entities in total)
Functional Keywords	class i and ii terpene cyclase fold, class ii diterpene cyclase, dxdd motif, gibberellin biosynthesis, biosynthesis of ent-copalyl diphosphate, isomerase
Biological source	Arabidopsis thaliana (mouse-ear cress,thale-cress)
Cellular location	Plastid, chloroplast: Q38802
Total number of polymer chains	1
Total formula weight	85512.84
Authors	Koksal, M.,Christianson, D.W. (deposition date: 2013-07-04, release date: 2013-10-02, Last modification date: 2023-12-06)
Primary citation	Koksal, M.,Potter, K.,Peters, R.J.,Christianson, D.W. 1.55 angstrom -resolution structure of ent-copalyl diphosphate synthase and exploration of general acid function by site-directed mutagenesis. Biochim.Biophys.Acta, 1840:184-190, 2013 Cited by PubMed: 24036329 DOI: 10.1016/j.bbagen.2013.09.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.548 Å)

Structure validation