4LCW

The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH

Summary for 4LCW

• Entry DOI: 10.2210/pdb4lcw/pdb
• Related: 4L4V
• Descriptor: Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, MAIT T cell receptor alpha chain, ... (7 entities in total)
• Functional Keywords: mhc class i-related protein, mait t cell receptor, vitamin b2 metabolites, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Single-pass membrane protein; Extracellular side. Isoform 4: Secreted: Q95460; Secreted: P61769
• Total number of polymer chains: 8
• Total formula weight: 187945.37

Authors

Patel, O.,Rossjohn, J. (deposition date: 2013-06-24, release date: 2013-10-02, Last modification date: 2023-09-20)

• Primary citation: Reantragoon, R.,Corbett, A.J.,Sakala, I.G.,Gherardin, N.A.,Furness, J.B.,Chen, Z.,Eckle, S.B.,Uldrich, A.P.,Birkinshaw, R.W.,Patel, O.,Kostenko, L.,Meehan, B.,Kedzierska, K.,Liu, L.,Fairlie, D.P.,Hansen, T.H.,Godfrey, D.I.,Rossjohn, J.,McCluskey, J.,Kjer-Nielsen, L.; Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells.; J.Exp.Med., 210:2305-2320, 2013; PubMed: 24101382; DOI: 10.1084/jem.20130958

Experimental method

X-RAY DIFFRACTION (2.4 Å)