4L6R

Structure of the class B human glucagon G protein coupled receptor

4L6R の概要

• エントリーDOI: 10.2210/pdb4l6r/pdb
• 分子名称: Soluble cytochrome b562 and Glucagon receptor chimera, DI(HYDROXYETHYL)ETHER (2 entities in total)
• 機能のキーワード: human glucagon receptor, diabetes, gpcr network, psi-biology, membrane protein, novel protein engineering, structural genomics, protein structure initiative, gpcr, membrane
• 由来する生物種: Escherichia coli (human); 詳細
• 細胞内の位置: Cell membrane ; Multi-pass membrane protein : P47871
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48256.96

構造登録者

Siu, F.Y.,He, M.,de Graaf, C.,Han, G.W.,Yang, D.,Zhang, Z.,Zhou, C.,Xu, Q.,Wacker, D.,Joseph, J.S.,Liu, W.,Lau, J.,Cherezov, V.,Katritch, V.,Wang, M.W.,Stevens, R.C.,GPCR Network (GPCR) (登録日: 2013-06-12, 公開日: 2013-07-24, 最終更新日: 2023-09-20)

• 主引用文献: Siu, F.Y.,He, M.,de Graaf, C.,Han, G.W.,Yang, D.,Zhang, Z.,Zhou, C.,Xu, Q.,Wacker, D.,Joseph, J.S.,Liu, W.,Lau, J.,Cherezov, V.,Katritch, V.,Wang, M.W.,Stevens, R.C.; Structure of the human glucagon class B G-protein-coupled receptor.; Nature, 499:444-449, 2013; PubMed: 23863937; DOI: 10.1038/nature12393

実験手法

X-RAY DIFFRACTION (3.3 Å)