4L57

High resolutin structure of human cytosolic 5'(3')-deoxyribonucleotidase

Summary for 4L57

Entry DOI	10.2210/pdb4l57/pdb
Descriptor	5'(3')-deoxyribonucleotidase, cytosolic type, MAGNESIUM ION, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	5'-nucleotidase, protein conformation, sequence homology, had-like, hydrolase, dephosphorylation
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q8TCD5
Total number of polymer chains	2
Total formula weight	46424.43
Authors	Pachl, P.,Brynda, J.,Rezacova, P. (deposition date: 2013-06-10, release date: 2014-02-12, Last modification date: 2024-02-28)
Primary citation	Pachl, P.,Fabry, M.,Rosenberg, I.,Simak, O.,Rezacova, P.,Brynda, J. Structures of human cytosolic and mitochondrial nucleotidases: implications for structure-based design of selective inhibitors. Acta Crystallogr. D Biol. Crystallogr., 70:461-470, 2014 Cited by PubMed: 24531480 DOI: 10.1107/S1399004713030502 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.08 Å)

Structure validation