4L29

Structure of wtMHC class I with NY-ESO1 double mutant

Summary for 4L29

• Entry DOI: 10.2210/pdb4l29/pdb
• Related: 4L3C
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, NY-ESO1 DOUBLE MUTANT (1Y, 9V), ... (6 entities in total)
• Functional Keywords: mhc, beta-2 microglobulin, hla_a0201, ny-eso1, d76n variant, immunglobulin, beta sandwitch, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• Total number of polymer chains: 42
• Total formula weight: 632864.91

Authors

Halabelian, L.,Giorgetti, S.,Bellotti, V.,Bolognesi, M.,Ricagno, S. (deposition date: 2013-06-04, release date: 2013-12-25, Last modification date: 2014-02-26)

• Primary citation: Halabelian, L.,Ricagno, S.,Giorgetti, S.,Santambrogio, C.,Barbiroli, A.,Pellegrino, S.,Achour, A.,Grandori, R.,Marchese, L.,Raimondi, S.,Mangione, P.P.,Esposito, G.,Al-Shawi, R.,Simons, J.P.,Speck, I.,Stoppini, M.,Bolognesi, M.,Bellotti, V.; Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.; J.Biol.Chem., 289:3318-3327, 2014; PubMed: 24338476; DOI: 10.1074/jbc.M113.524157

Experimental method

X-RAY DIFFRACTION (3.09 Å)