4KYI

Crystal structure of the phospholipase VipD from Legionella pneumophila in complex with the human GTPase Rab5

Summary for 4KYI

Entry DOI	10.2210/pdb4kyi/pdb
Descriptor	VipD, Ras-related protein Rab-5C, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	phospholipase, protein binding-transport protein complex, protein binding/transport protein
Biological source	Legionella pneumophila subsp. pneumophila More
Cellular location	Cell membrane ; Lipid-anchor ; Cytoplasmic side : P51148
Total number of polymer chains	8
Total formula weight	322919.41
Authors	Lucas, M.,Gaspar, A.H.,Pallara, C.,Rojas, A.L.,Fernandez-Recio, J.,Machner, M.P.,Hierro, A. (deposition date: 2013-05-29, release date: 2014-08-13, Last modification date: 2015-07-29)
Primary citation	Lucas, M.,Gaspar, A.H.,Pallara, C.,Rojas, A.L.,Fernandez-Recio, J.,Machner, M.P.,Hierro, A. Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5. Proc.Natl.Acad.Sci.USA, 111:E3514-E3523, 2014 Cited by PubMed: 25114243 DOI: 10.1073/pnas.1405391111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.075 Å)

Structure validation