4KXO

Crystal Structure of BBBB at pH 10.0 with MPD as the cryoprotectant

Summary for 4KXO

Entry DOI	10.2210/pdb4kxo/pdb
Descriptor	Histo-blood group ABO system transferase (2 entities in total)
Functional Keywords	manganese, abo rossmann fold, retaining glycosyltransferase, blood group antigen, metal-binding, glycoprotein, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	34009.27
Authors	Johal, A.R.,Blackler, R.J.,Alfaro, J.A.,Schuman, B.,Borisova, S.N.,Evans, S.V. (deposition date: 2013-05-27, release date: 2014-04-09, Last modification date: 2023-09-20)
Primary citation	Johal, A.R.,Blackler, R.J.,Alfaro, J.A.,Schuman, B.,Borisova, S.,Evans, S.V. pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24:237-246, 2014 Cited by PubMed: 24265507 DOI: 10.1093/glycob/cwt098 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation