4KUX

Crystal structure of Aspergillus terreus aristolochene synthase complexed with farnesyl thiolodiphosphate (FSPP)

Summary for 4KUX

Entry DOI	10.2210/pdb4kux/pdb
Related	3BNY 4KVD 4KVI
Descriptor	Aristolochene synthase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... (5 entities in total)
Functional Keywords	class i terpene cyclase, lyase
Biological source	Aspergillus terreus
Total number of polymer chains	4
Total formula weight	146955.00
Authors	Chen, M.,Faraldos, J.A.,Al-lami, N.,Janvier, M.,D'Antonio, E.L.,Cane, D.E.,Allemann, R.K.,Christianson, D.W. (deposition date: 2013-05-22, release date: 2013-08-14, Last modification date: 2023-09-20)
Primary citation	Chen, M.,Al-Lami, N.,Janvier, M.,D'Antonio, E.L.,Faraldos, J.A.,Cane, D.E.,Allemann, R.K.,Christianson, D.W. Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase. Biochemistry, 52:5441-5453, 2013 Cited by PubMed: 23905850 DOI: 10.1021/bi400691v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation