4KRF
Structure of Human Argonaute-1 let-7 complex
Summary for 4KRF
Entry DOI | 10.2210/pdb4krf/pdb |
Related | 4KRE |
Descriptor | Protein argonaute-1, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3') (3 entities in total) |
Functional Keywords | eukaryotic argonaute, gene regulation, rnai, slicer, transcription-rna complex, transcription/rna |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, P-body: Q9UL18 |
Total number of polymer chains | 2 |
Total formula weight | 104538.58 |
Authors | Faehnle, C.R.,Elkayam, E.,Joshua-Tor, L. (deposition date: 2013-05-16, release date: 2013-06-19, Last modification date: 2024-02-28) |
Primary citation | Faehnle, C.R.,Elkayam, E.,Haase, A.D.,Hannon, G.J.,Joshua-Tor, L. The making of a slicer: activation of human argonaute-1. Cell Rep, 3:1901-1909, 2013 Cited by PubMed: 23746446DOI: 10.1016/j.celrep.2013.05.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.101 Å) |
Structure validation
Download full validation report