4KGG
Crystal structure of light mutant2 and dcr3 complex
Summary for 4KGG
| Entry DOI | 10.2210/pdb4kgg/pdb |
| Related | 3K51 3MHD 3MI8 4EN0 4J6G |
| Descriptor | Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 14, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
| Functional Keywords | light, dcr3, tnf, tnfr, tnf14, structural genomics, psi-biology, new hvem, n-glycosylation, membrane, secreted protein, cytokine, ifn, jelly-roll fold, bind tnf receptor hvem and ltbr, ltbr, protein structure initiative, atoms-to-animals: the immune function network, new york structural genomics research consortium, nysgrc, immune system, cytokine-signaling protein complex, cytokine/signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 73727.00 |
| Authors | Liu, W.,Bonanno, J.B.,Zhan, C.,Kumar, P.R.,Toro, R.,Nathenson, S.G.,Almo, S.C.,Atoms-to-Animals: The Immune Function Network (IFN),New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2013-04-29, release date: 2013-08-07, Last modification date: 2023-09-20) |
| Primary citation | Liu, W.,Zhan, C.,Cheng, H.,Kumar, P.R.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C. Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly. Structure, 22:1252-1262, 2014 Cited by PubMed: 25087510DOI: 10.1016/j.str.2014.06.013 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
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