4KDP

TcaR-ssDNA complex crystal structure reveals the novel ssDNA binding mechanism of the MarR family proteins

Summary for 4KDP

• Entry DOI: 10.2210/pdb4kdp/pdb
• Descriptor: TcaR transcription regulator, DNA (5'-D(*CP*GP*CP*AP*GP*CP*GP*CP*GP*CP*AP*GP*CP*CP*CP*TP*A)-3'), 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: multiple drug resistance, ssdna binding, antibiotics, staphylococci, transcription-dna complex, transcription/dna
• Biological source: Staphylococcus epidermidis
• Total number of polymer chains: 9
• Total formula weight: 132947.17

Authors

Chang, Y.M.,Chen, C.K.-M.,Wang, A.H.-J. (deposition date: 2013-04-25, release date: 2014-03-19, Last modification date: 2023-09-20)

• Primary citation: Chang, Y.M.,Ho, C.H.,Chen, C.K.,Maestre-Reyna, M.,Chang-Chien, M.W.,Wang, A.H.; TcaR-ssDNA complex crystal structure reveals new DNA binding mechanism of the MarR family proteins.; Nucleic Acids Res., 42:5314-5321, 2014; PubMed: 24531929; DOI: 10.1093/nar/gku128

Experimental method

X-RAY DIFFRACTION (3.6 Å)