4K80

Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 2:0 ceramide-1-phosphate (2:0-C1P)

Summary for 4K80

Entry DOI	10.2210/pdb4k80/pdb
Related	4K84 4K85 4K8N 4KBR 4KBS 4KF6
Descriptor	Glycolipid transfer protein domain-containing protein 1, (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate (3 entities in total)
Functional Keywords	lipid transfer protein, gltp-fold, cptp, c1p, ceramide-1-phosphate, protein-lipid complex, eicosanoid, lipid transport
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytosol : Q5TA50
Total number of polymer chains	1
Total formula weight	24905.66
Authors	Simanshu, D.K.,Brown, R.E.,Patel, D.J. (deposition date: 2013-04-17, release date: 2013-07-17, Last modification date: 2024-04-03)
Primary citation	Simanshu, D.K.,Kamlekar, R.K.,Wijesinghe, D.S.,Zou, X.,Zhai, X.,Mishra, S.K.,Molotkovsky, J.G.,Malinina, L.,Hinchcliffe, E.H.,Chalfant, C.E.,Brown, R.E.,Patel, D.J. Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500:463-467, 2013 Cited by PubMed: 23863933 DOI: 10.1038/nature12332 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.051 Å)

Structure validation