4K78
CFTR Associated Ligand (CAL) E317A PDZ domain bound to peptide iCAL36-QDTRL (ANSRWQDTRL)
Summary for 4K78
| Entry DOI | 10.2210/pdb4k78/pdb |
| Related | 4K6Y 4K72 4K75 4K76 |
| Descriptor | Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-QDTRL peptide (3 entities in total) |
| Functional Keywords | pdz domain, cal, pist, fig, pdz-peptide complex, cftr associated ligand, cftr, peptide binding protein-protein binding complex, peptide binding protein/protein binding |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q9HD26 |
| Total number of polymer chains | 2 |
| Total formula weight | 10624.10 |
| Authors | Amacher, J.F.,Madden, D.R. (deposition date: 2013-04-16, release date: 2014-01-22, Last modification date: 2023-09-20) |
| Primary citation | Amacher, J.F.,Cushing, P.R.,Brooks, L.,Boisguerin, P.,Madden, D.R. Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses. Structure, 22:82-93, 2014 Cited by PubMed: 24210758DOI: 10.1016/j.str.2013.09.019 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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