4K4T

Poliovirus polymerase elongation complex (r4_form)

Summary for 4K4T

• Entry DOI: 10.2210/pdb4k4t/pdb
• Related: 1RA6 3ol6 4K4S 4K4U 4K4V 4K4W 4K4X 4K4Y 4K4Z 4K50
• Descriptor: RNA-directed RNA polymerase 3D-POL, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*GP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*UP*UP*CP*CP*GP*AP*GP*AP*GP*A)-3'), ... (7 entities in total)
• Functional Keywords: polymerase, rna-dependent rna polymerase, protein-rna complex, transferase-rna complex, transferase/rna
• Biological source: Human poliovirus 1
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300
• Total number of polymer chains: 8
• Total formula weight: 135712.43

Authors

Gong, P.,Peersen, O.B. (deposition date: 2013-04-12, release date: 2013-05-22, Last modification date: 2024-02-28)

• Primary citation: Gong, P.,Kortus, M.G.,Nix, J.C.,Davis, R.E.,Peersen, O.B.; Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.; Plos One, 8:e60272-e60272, 2013; PubMed: 23667424; DOI: 10.1371/journal.pone.0060272

Experimental method

X-RAY DIFFRACTION (2.75 Å)