4JVP

Three dimensional structure of broadly neutralizing anti - Hepatitis C virus (HCV) glycoprotein E2 alpaca nanobody D03

Summary for 4JVP

• Entry DOI: 10.2210/pdb4jvp/pdb
• Descriptor: Anti-HCV E2 alpaca nanobody D03, SULFATE ION (3 entities in total)
• Functional Keywords: heavy-chain antibody, nanobody, immunoglobulin fold, antibody, immune system
• Biological source: Vicugna pacos (alpaca)
• Total number of polymer chains: 2
• Total formula weight: 32087.08

Authors

Krey, T.,Rey, F.A. (deposition date: 2013-03-26, release date: 2013-04-24, Last modification date: 2023-09-20)

• Primary citation: Tarr, A.W.,Lafaye, P.,Meredith, L.,Damier-Piolle, L.,Urbanowicz, R.A.,Meola, A.,Jestin, J.L.,Brown, R.J.,McKeating, J.A.,Rey, F.A.,Ball, J.K.,Krey, T.; An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission.; Hepatology, 58:932-939, 2013; PubMed: 23553604; DOI: 10.1002/hep.26430

Experimental method

X-RAY DIFFRACTION (1.76 Å)