4JV2

Ternary complex of gamma-OHPDG adduct modified dna with dna (-1 primer) polymerase iv and incoming datp

Summary for 4JV2

• Entry DOI: 10.2210/pdb4jv2/pdb
• Related: 4JUZ 4JV0 4JV1
• Descriptor: DNA polymerase IV, DNA (5'-D(P*TP*(HN1)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... (6 entities in total)
• Functional Keywords: ternary complex of dpo4-dna-datp, dna polymerase, dna adduct, transferase-dna complex, transferase/dna
• Biological source: Sulfolobus solfataricus
• Cellular location: Cytoplasm (Probable): Q97W02
• Total number of polymer chains: 3
• Total formula weight: 49153.54

Authors

Banerjee, S.,Shanmugam, G.,Stone, M.P. (deposition date: 2013-03-25, release date: 2013-08-28, Last modification date: 2024-02-28)

• Primary citation: Shanmugam, G.,Minko, I.G.,Banerjee, S.,Christov, P.P.,Kozekov, I.D.,Rizzo, C.J.,Lloyd, R.S.,Egli, M.,Stone, M.P.; Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4.; Chem.Res.Toxicol., 26:1348-1360, 2013; PubMed: 23947567; DOI: 10.1021/tx400200b

Experimental method

X-RAY DIFFRACTION (2.74 Å)