4JPJ

Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6

Summary for 4JPJ

Entry DOI	10.2210/pdb4jpj/pdb
Related	4JPI 4JPK
Descriptor	Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	hiv-1 gp120, cd4 binding site, vrc01-like broadly neutralizing antibodies, viral protein
Biological source	Human immunodeficiency virus 1 (HIV-1)
Total number of polymer chains	4
Total formula weight	81774.25
Authors	Julien, J.-P.,Jardine, J.,Schief, W.R.,Wilson, I.A. (deposition date: 2013-03-19, release date: 2013-04-10, Last modification date: 2023-09-20)
Primary citation	Jardine, J.,Julien, J.P.,Menis, S.,Ota, T.,Kalyuzhniy, O.,McGuire, A.,Sok, D.,Huang, P.S.,MacPherson, S.,Jones, M.,Nieusma, T.,Mathison, J.,Baker, D.,Ward, A.B.,Burton, D.R.,Stamatatos, L.,Nemazee, D.,Wilson, I.A.,Schief, W.R. Rational HIV immunogen design to target specific germline B cell receptors. Science, 340:711-716, 2013 Cited by PubMed: 23539181 DOI: 10.1126/science.1234150 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation