4JMH

Crystal structure of synthetic protein in complex with double pY peptide

Summary for 4JMH

• Entry DOI: 10.2210/pdb4jmh/pdb
• Related: 4JMG
• Descriptor: Clamp Shc1_pY239/240, SHC-transforming protein 1 (3 entities in total)
• Functional Keywords: synthetic protein, binding to double py containing sequence, de novo protein
• Biological source: synthetic construct; More
• Cellular location: Cytoplasm. Isoform p46Shc: Mitochondrion matrix. Isoform p66Shc: Mitochondrion (By similarity): P29353
• Total number of polymer chains: 2
• Total formula weight: 24073.54

Authors

Yasui, N.,Smith, L.,Koide, S. (deposition date: 2013-03-14, release date: 2014-04-23, Last modification date: 2023-12-06)

• Primary citation: Yasui, N.,Findlay, G.M.,Gish, G.D.,Hsiung, M.S.,Huang, J.,Tucholska, M.,Taylor, L.,Smith, L.,Boldridge, W.C.,Koide, A.,Pawson, T.,Koide, S.; Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.; Mol.Cell, 54:1034-1041, 2014; PubMed: 24910098; DOI: 10.1016/j.molcel.2014.05.002

Experimental method

X-RAY DIFFRACTION (2.408 Å)