4JIJ
Crystal structure of an inactive mutant of MMP-9 catalytic domain in complex with a fluorogenic synthetic peptidic substrate
Summary for 4JIJ
Entry DOI | 10.2210/pdb4jij/pdb |
Related | 2OW0 2OW1 4H1Q 4H2E 4H3X 4H82 4HMA 4JQG 4JXA |
Descriptor | fluorogenic peptidic substrate (8MC)PLG(PHI)(DNW)AR(NH2), GLYCEROL, Matrix metalloproteinase-9, ... (11 entities in total) |
Functional Keywords | hydrolase substrate complex, zincin-like, gelatinase, collagenase, catalytic domain, hydrolase-substrate complex, hydrolase/substrate |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space, extracellular matrix : P14780 |
Total number of polymer chains | 4 |
Total formula weight | 40533.77 |
Authors | Stura, E.A.,Vera, L.,Cassar-Lajeunesse, E.,Tranchant, I.,Amoura, M.,Dive, V. (deposition date: 2013-03-06, release date: 2014-03-12, Last modification date: 2023-12-06) |
Primary citation | Tranchant, I.,Vera, L.,Czarny, B.,Amoura, M.,Cassar, E.,Beau, F.,Stura, E.A.,Dive, V. Halogen Bonding Controls Selectivity of FRET Substrate Probes for MMP-9. Chem.Biol., 21:408-413, 2014 Cited by PubMed: 24583051DOI: 10.1016/j.chembiol.2014.01.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.698 Å) |
Structure validation
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