4JFQ

A2 HLA complex with L8A heteroclitic variant of Melanoma peptide

Summary for 4JFQ

Entry DOI	10.2210/pdb4jfq/pdb
Related	4JFD 4JFE 4JFF 4JFH 4JFO 4JFP
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, L8A heteroclitic Melanoma peptide, ... (6 entities in total)
Functional Keywords	immunoglobulin, hla, tcr, melanoma, immune system, high affinity
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769
Total number of polymer chains	6
Total formula weight	91687.80
Authors	Rizkallah, P.J.,Cole, D.K.,Madura, F.,Sewell, A.K.,Baker, B.M. (deposition date: 2013-02-28, release date: 2013-05-29, Last modification date: 2013-07-17)
Primary citation	Madura, F.,Rizkallah, P.J.,Miles, K.M.,Holland, C.J.,Bulek, A.M.,Fuller, A.,Schauenburg, A.J.,Miles, J.J.,Liddy, N.,Sami, M.,Li, Y.,Hossain, M.,Baker, B.M.,Jakobsen, B.K.,Sewell, A.K.,Cole, D.K. T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288:18766-18775, 2013 Cited by PubMed: 23698002 DOI: 10.1074/jbc.M113.464560 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation