4JCK
Galectin-3 carbohydrate recognition domain in complex with thioditaloside
Summary for 4JCK
| Entry DOI | 10.2210/pdb4jck/pdb |
| Related | 4JC1 |
| Related PRD ID | PRD_900109 |
| Descriptor | Galectin-3, beta-D-talopyranose-(1-1)-1-thio-beta-D-talopyranose, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | beta sandwich, carbohydrate binding protein, sugar binding protein-inhibitor complex, sugar binding protein/inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 16448.24 |
| Authors | Bum-Erdene, K.,Blanchard, H. (deposition date: 2013-02-22, release date: 2013-07-31, Last modification date: 2024-02-28) |
| Primary citation | Bum-Erdene, K.,Gagarinov, I.A.,Collins, P.M.,Winger, M.,Pearson, A.G.,Wilson, J.C.,Leffler, H.,Nilsson, U.J.,Grice, I.D.,Blanchard, H. Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors. Chembiochem, 14:1331-1342, 2013 Cited by PubMed: 23864426DOI: 10.1002/cbic.201300245 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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