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4JC1

Galectin-3 carbohydrate recognition domain in complex with thiodigalactoside

Summary for 4JC1
Entry DOI10.2210/pdb4jc1/pdb
Related4JCK
Related PRD IDPRD_900027
DescriptorGalectin-3, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsbeta sandwich, carbohydrate binding protein, sugar binding protein
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight16590.05
Authors
Collins, P.M.,Blanchard, H. (deposition date: 2013-02-21, release date: 2013-07-31, Last modification date: 2023-09-20)
Primary citationBum-Erdene, K.,Gagarinov, I.A.,Collins, P.M.,Winger, M.,Pearson, A.G.,Wilson, J.C.,Leffler, H.,Nilsson, U.J.,Grice, I.D.,Blanchard, H.
Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors.
Chembiochem, 14:1331-1342, 2013
Cited by
PubMed: 23864426
DOI: 10.1002/cbic.201300245
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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