4JBR

tRNA-guanine transglycosylase Y330C mutant as covalently linked dimer in space group P6(5)22

Summary for 4JBR

• Entry DOI: 10.2210/pdb4jbr/pdb
• Related: 1PUD 3UNT 3UVI 4DXX 4DY1 4HTB
• Descriptor: tRNA-guanine transglycosylase, ZINC ION, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: covalent dimer, tim-barrel, transferase, guanine, preq1, trna
• Biological source: Zymomonas mobilis subsp. mobilis
• Total number of polymer chains: 1
• Total formula weight: 43153.34

Authors

Jakobi, S.,Klebe, G. (deposition date: 2013-02-20, release date: 2014-03-19, Last modification date: 2023-09-20)

• Primary citation: Nguyen, D.,Xie, X.,Jakobi, S.,Terwesten, F.,Metz, A.,Nguyen, T.X.P.,Palchykov, V.A.,Heine, A.,Reuter, K.,Klebe, G.; Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface.; Acs Chem.Biol., 16:1090-1098, 2021; PubMed: 34081441; DOI: 10.1021/acschembio.1c00296

Experimental method

X-RAY DIFFRACTION (2.92 Å)