4J83

SET7/9 in complex with TAF10K189A peptide and AdoMet

Summary for 4J83

• Entry DOI: 10.2210/pdb4j83/pdb
• Related: 1N6A 3M53 4J8O
• Descriptor: Histone-lysine N-methyltransferase SETD7, Transcription initiation factor TFIID subunit 10, S-ADENOSYLMETHIONINE, ... (4 entities in total)
• Functional Keywords: set domain, lysine methyltransferase, transferase-peptide complex, transferase/peptide
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q8WTS6 Q12962
• Total number of polymer chains: 2
• Total formula weight: 30639.13

Authors

Horowitz, S.,Nimtz, J.S.,Trievel, R.C. (deposition date: 2013-02-14, release date: 2014-01-08, Last modification date: 2024-02-28)

• Primary citation: Horowitz, S.,Dirk, L.M.,Yesselman, J.D.,Nimtz, J.S.,Adhikari, U.,Mehl, R.A.,Scheiner, S.,Houtz, R.L.,Al-Hashimi, H.M.,Trievel, R.C.; Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases.; J.Am.Chem.Soc., 135:15536-15548, 2013; PubMed: 24093804; DOI: 10.1021/ja407140k

Experimental method

X-RAY DIFFRACTION (1.7 Å)