4IUO

1.8 Angstrom Crystal Structure of the Salmonella enterica 3-Dehydroquinate Dehydratase (aroD) K170M Mutant in Complex with Quinate

Summary for 4IUO

Entry DOI	10.2210/pdb4iuo/pdb
Related	4GUI 4GUJ
Descriptor	3-dehydroquinate dehydratase, (1S,3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid (3 entities in total)
Functional Keywords	structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, tim barrel, lyase
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium
Total number of polymer chains	2
Total formula weight	60590.98
Authors	Light, S.H.,Minasov, G.,Duban, M.-E.,Shuvalova, L.,Kwon, K.,Lavie, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2013-01-21, release date: 2013-01-30, Last modification date: 2023-09-20)
Primary citation	Light, S.H.,Antanasijevic, A.,Krishna, S.N.,Caffrey, M.,Anderson, W.F.,Lavie, A. Crystal structures of type I dehydroquinate dehydratase in complex with quinate and shikimate suggest a novel mechanism of schiff base formation. Biochemistry, 53:872-880, 2014 Cited by PubMed: 24437575 DOI: 10.1021/bi4015506 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation