4IS8
Divergent sequence tunes ligand sensitivity in phospholipid-regulated hormone receptors
Summary for 4IS8
Entry DOI | 10.2210/pdb4is8/pdb |
Descriptor | Nuclear receptor subfamily 5 group A member 2 (2 entities in total) |
Functional Keywords | ligand binding domain, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Probable): O00482 |
Total number of polymer chains | 2 |
Total formula weight | 55690.27 |
Authors | Musille, P.M.,Pathak, M.C.,Ortlund, E.A. (deposition date: 2013-01-16, release date: 2013-06-12, Last modification date: 2024-02-28) |
Primary citation | Musille, P.M.,Pathak, M.,Lauer, J.L.,Griffin, P.R.,Ortlund, E.A. Divergent Sequence Tunes Ligand Sensitivity in Phospholipid-regulated Hormone Receptors. J.Biol.Chem., 288:20702-20712, 2013 Cited by PubMed: 23737522DOI: 10.1074/jbc.M113.472837 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
Download full validation report