4IRV
Structure of the Helicobacter pylori CagA Oncogene Bound to the Human Tumor Suppressor Apoptosis-stimulating Protein of p53-2
Summary for 4IRV
| Entry DOI | 10.2210/pdb4irv/pdb |
| Descriptor | Cytotoxicity-associated immunodominant antigen, Apoptosis-stimulating of p53 protein 2 (3 entities in total) |
| Functional Keywords | virulence factor and tumor suppressor, protein binding |
| Biological source | Helicobacter pylori More |
| Cellular location | Cytoplasm, perinuclear region: Q13625 |
| Total number of polymer chains | 8 |
| Total formula weight | 128357.34 |
| Authors | Stebbins, C.E.,Nesic, D. (deposition date: 2013-01-15, release date: 2014-01-15, Last modification date: 2015-02-25) |
| Primary citation | Nesic, D.,Buti, L.,Lu, X.,Stebbins, C.E. Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2. Proc.Natl.Acad.Sci.USA, 111:1562-1567, 2014 Cited by PubMed: 24474782DOI: 10.1073/pnas.1320631111 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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